EARLY FUNCTIONAL RECOVERY AFTER LAPAROSCOPIC SURGERY FOLLOWING NEOADJUVANT CHEMOTHERAPY IN STAGE III GASTRIC CANCER
- Authors
-
-
Abbos Oybek ugli Abdukodirov
Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology, Tashkent, Uzbekistan
Author
-
- Keywords:
- Gastric cancer, stage III, laparoscopic gastrectomy, neoadjuvant chemotherapy, functional recovery, hospital stay, postoperative pain.
- Abstract
-
Background: Surgery remains the cornerstone of curative treatment for locally advanced gastric cancer. In stage III disease, surgical treatment is often combined with neoadjuvant chemotherapy. However, surgery after neoadjuvant treatment may be technically more demanding, and the role of laparoscopic surgery in this setting remains clinically relevant.
Objective: To evaluate early functional recovery and short-term surgical outcomes after laparoscopic gastrectomy following neoadjuvant chemotherapy in patients with stage III gastric cancer. - References
-
1.Al-Batran SE, Homann N, Pauligk C, et al. Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma: a randomized phase 2/3 trial. Lancet Oncology. 2019;20(5):681–692.
2.Cunningham D, Allum WH, Stenning SP, et al. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. New England Journal of Medicine. 2006;355(1):11–20.
3.Noh SH, Park SR, Yang HK, et al. Adjuvant capecitabine plus oxaliplatin for gastric cancer after D2 gastrectomy: 5-year follow-up of a randomized phase 3 trial. Lancet Oncology. 2014;15(12):1389–1396.
4.
Son SY, Lee CM, Ahn SH, et al. Laparoscopic versus open distal gastrectomy for locally advanced gastric cancer: 5-year outcomes of the KLASS-02 randomized clinical trial. JAMA Surgery. 2022;157(10):879–886.
5.Etoh T, Ohyama T, Sakuramoto S, et al. Five-year survival outcomes of laparoscopy-assisted versus open distal gastrectomy for advanced gastric cancer: the JLSSG0901 randomized clinical trial. JAMA Surgery. 2023;158(5):445–454.
6.Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients. Annals of Surgery. 2004;240(2):205–213.
7.Japanese Gastric Cancer Association. Japanese gastric cancer treatment guidelines 2021. Gastric Cancer. 2023;26(1):1–25.
8.Kitano S, Shiraishi N, Uyama I, Sugihara K, Tanigawa N. A multicenter study on oncologic outcome of laparoscopic gastrectomy for early cancer in Japan. Annals of Surgery. 2007;245(1):68–72.
- Downloads
- Published
- 2026-06-09
- Issue
- Vol. 2 No. 6 (2026)
- Section
- Articles
- License
-
This work is licensed under a Creative Commons Attribution 4.0 International License.
