ADVANCES IN THE MANAGEMENT OF KIDNEY DYSFUNCTION ASSOCIATED WITH HYPOTHYROIDISM: FROM HORMONE REPLACEMENT TO PERSONALIZED THERAPY
- Authors
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Karimova Ohistabonu Abrorovna
Endocrinologist, Fergana Branch of the Republican Specialized Scientific and Practical Medical Center of Endocrinology, Uzbekistan Assistant, Department of Phthisiology, Pulmonology and Metabolic Diseases, Central Asian Medical University (CAMU), Uzbekistan
Author
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- Keywords:
- Hypothyroidism, renal dysfunction, chronic kidney disease, levothyroxine, personalized therapy, kidney function, nephrology, endocrinology
- Abstract
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Kidney dysfunction associated with hypothyroidism has become an increasingly recognized clinical entity in modern endocrinology and nephrology. Thyroid hormones play a fundamental role in maintaining renal hemodynamics, glomerular filtration, tubular transport processes, electrolyte balance, and cardiovascular stability. Deficiency of thyroid hormones may result in reduced renal blood flow, decreased glomerular filtration rate, elevated serum creatinine levels, sodium retention, and progressive impairment of renal function. Importantly, many of these abnormalities are potentially reversible following adequate thyroid hormone replacement therapy. Despite growing evidence supporting the association between hypothyroidism and renal dysfunction, diagnostic delays and underrecognition remain common in routine clinical practice.
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- Published
- 2026-06-09
- Issue
- Vol. 2 No. 6 (2026)
- Section
- Articles
- License
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This work is licensed under a Creative Commons Attribution 4.0 International License.
