STUDY OF THE FUNCTIONAL STATE OF THE THYROID GLAND AND DISEASES OF ITS PARENCHYMA IN WOMEN WITH METABOLIC SYNDROME
- Authors
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Karimova Muqima Mukhammadsodiqovna
PhD, Associate Professor, Head of the Department of Endocrinology, Hematology and Phthisiology, Fergana Medical Institute of Public Health, Fergana, Uzbekistan
Author
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Oltinboeva Zarnigor Avazbek qizi
Assistant Lecturer, Department of Endocrinology, Hematology and Phthisiology, Fergana Medical Institute of Public Health, Fergana, Uzbekistan
Author
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- Keywords:
- Thyroid gland, thyroiditis, hypothyroidism, nodular goiter, metabolic syndrome.
- Abstract
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This article evaluates the functional state of the thyroid gland (TG) in women with metabolic syndrome through hormonal examinations, as well as pathological changes in the TG tissue using ultrasound and histological analysis. According to the results obtained, an increase in thyroid volume was observed in Group 1 (150 women with metabolic syndrome) compared to the control group: Grade I goiter was recorded in 37.3% of cases, and Grade II goiter in 62.7% of cases. Analysis of the functional state of the TG confirmed that cases of subclinical and overt hypothyroidism were significantly higher in women of Group 1 compared to Group 2 (women without metabolic syndrome).
- References
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1.Dedov I.I., Melnichenko G.A., Fadeev V.V. Endocrinology: National Guidelines. — Moscow: GEOTAR-Media, 2021. — 832 p. (For general classification and treatment standards of endocrine diseases).
2.Gafurov A.A., Karimova M.M. "Correlation between Iodine Deficiency and Thyroid Pathologies". // Bulletin of Fergana Medicine, 2025. — No. 2. — P. 45-48. (To highlight the characteristics of local endemic regions).
3.Biondi B., Cooper D.S. "Thyroid Disorders in Patients with Metabolic Syndrome". // Journal of Clinical Endocrinology & Metabolism, 2024. — Vol. 109, Issue 4. — P. 112-125. (Fundamental source on the relationship between metabolic syndrome and thyroid hormones).
4.Aversa A., et al. "Metabolic Syndrome and Thyroid Function: Evidence-based links". // Endocrine Reviews, 2023. — No. 44 (2). — P. 340-358. (Regarding insulin resistance and thyroid gland proliferation).
5.Ministry of Health of the Republic of Uzbekistan. "Clinical Protocols for the Diagnosis and Treatment of Thyroid Diseases". — Tashkent, 2024. (For the regulatory and legal framework).
6.Kim H.J., et al. "Association between subclinical hypothyroidism and metabolic syndrome". // Thyroid Research, 2025. — No. 18 (1). — P. 22-29. (Regarding the correlation of subclinical hypothyroidism with MS).
7.Petrukhin V.A. "Metabolic Syndrome and Endocrine Disorders in Women". // Obstetrics and Gynecology, 2024. — No. 5. — P. 88-94. (Clinical analysis of metabolic changes in women).
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- Published
- 2026-04-30
- Issue
- Vol. 2 No. 4 (2026)
- Section
- Articles
- License
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This work is licensed under a Creative Commons Attribution 4.0 International License.
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- Karimova Muqima Mukhammadsodiqovna, Oltinboeva Zarnigor Avazbek qizi, STUDY OF THE FUNCTIONAL STATE OF THE THYROID GLAND AND DISEASES OF ITS PARENCHYMA IN WOMEN WITH METABOLIC SYNDROME , Eureka Journal of Health Sciences & Medical Innovation: Vol. 2 No. 3 (2026)








