PREIMPLANTATION GENETIC TESTING FOR ANEUPLOIDY (PGT-A) AND NON-INVASIVE PRENATAL TESTING (NIPT) AS KEY COMPONENTS OF CONTEMPORARY PREGNANCY MANAGEMENT

Authors

  • Jurayev Islombek Izzatullo ugli 1st Year Clinical Resident, Obstetrics and Gynecology Author
  • Toshmurodova Yorkinoy Rustam kizi 2nd Year Clinical Resident, Obstetrics and Gynecology Author
  • Rakhmonova Mohigul Shodikulovna 1st Year Clinical Resident, Obstetrics and Gynecology Candidate of Medical Sciences, Professor Agababyan Larisa Rubenovna Head of the Department of Postgraduate Education in Obstetrics and Gynecology Author
  • Agababyan Larisa Rubenovna Candidate of Medical Sciences, Professor Head of the Department of Postgraduate Education in Obstetrics and Gynecology Author
  • Khudoyarova Dildora Rakhimovna Candidate of Medical Sciences, Professor Head of Department of Obstetrics and Gynecology No. 1 Samarkand State Medical University, Samarkand, Uzbekistan Author

Keywords:

In vitro fertilization, pregnancy management, diagnostic challenges, reproductive outcomes.

Abstract

The rapid development of reproductive genetics has substantially influenced current approaches to pregnancy planning and prenatal care. Preimplantation genetic testing for aneuploidy (PGT-A) and non-invasive prenatal testing (NIPT) are innovative screening methods designed to identify chromosomal abnormalities at different stages of human development. PGT-A is performed prior to embryo implantation during assisted reproductive technology cycles, while NIPT allows early assessment of fetal chromosomal status through maternal blood analysis. The combined use of these methods contributes to improved reproductive outcomes, reduction of pregnancy loss, and optimization of individualized pregnancy management. This article provides an analytical overview of the principles, clinical significance, advantages, limitations, and ethical aspects of PGT-A and NIPT in modern obstetric practice.

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Published

2026-01-22

Issue

Vol. 2 No. 1 (2026)

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

PREIMPLANTATION GENETIC TESTING FOR ANEUPLOIDY (PGT-A) AND NON-INVASIVE PRENATAL TESTING (NIPT) AS KEY COMPONENTS OF CONTEMPORARY PREGNANCY MANAGEMENT. (2026). Eureka Journal of Health Sciences & Medical Innovation, 2(1), 259-265. https://eurekaoa.com/index.php/5/article/view/219