INNOVATIVE NEUROFEEDBACK THERAPY FOR COGNITIVE IMPAIRMENT IN PATIENTS WITH CEREBROVASCULAR DISEASES
- Authors
-
-
Maqsudova X.N.
Tashkent State Medical University Uzbekistan
Author
-
- Keywords:
- cerebrovascular disease, neurofeedback, cognitive impairment, stroke rehabilitation, neurorehabilitation
- Abstract
-
Background: Cerebrovascular diseases remain one of the leading causes of long-term disability and reduced quality of life worldwide. Cognitive impairment following stroke is a common clinical problem that significantly affects patients’ functional independence. Objective: To evaluate the effectiveness of neurofeedback therapy as an adjunct to standard treatment in patients with cerebrovascular diseases. Methods: A prospective comparative study included 50 patients with cerebrovascular pathology who were treated at the private clinic “Neuromed Service” and the Central Clinical Hospital of JSC “Uzbekistan Railways”. Patients were divided into two groups: the control group receiving standard pharmacological therapy (n=25) and the experimental group receiving standard therapy combined with neurofeedback therapy (n=25). Cognitive functions were assessed using the MMSE and MoCA scales before and after a 10-day treatment course. Additional assessments included the Visual Analogue Scale (VAS).Results: Patients receiving neurofeedback therapy demonstrated significantly greater improvement in cognitive performance and reduction of neurological symptoms compared with those receiving conventional therapy alone (p < 0.001). The mean MMSE score increased from 24.7 ± 1.6 to 29.5 ± 1.4 in the neurofeedback group, while MoCA scores improved from 14.6 ± 2.1 to 18.0 ± 1.7. Patients also showed improvements in attention, emotional stability, and subjective well-being. Conclusion: Neurofeedback therapy may represent an effective adjunctive approach in the rehabilitation of patients with cerebrovascular diseases and may contribute to improved cognitive recovery and overall clinical outcomes.
- References
-
1. Arns M., de Ridder S., Strehl U., Breteler M., Coenen A. Neurofeedback as a treatment intervention in ADHD. Clin EEG Neurosci. 2009.
2. Markovska-Simoska S. Neurofeedback training for cognitive and behavioral improvement. 2008.
3. Feigin V.L., Norrving B., Mensah G.A. Global burden of stroke. Lancet Neurol. 2015.
4. Kakuda W., Abo M. Clinical applications of transcranial magnetic stimulation in stroke rehabilitation. 2012.
5. Laver K.E., Lange B., George S., Deutsch J.E., Saposnik G. Virtual reality for post-stroke rehabilitation. 2017.
6. Brunoni A.R. et al. Transcranial direct current stimulation in major depressive disorder. 2011.
7. Mijajlović M.D. et al. Cognitive impairment after stroke. 2017.
8. World Health Organization. Global Health Estimates. 2020.
9. Cicerone KD, et al. Evidence-based cognitive rehabilitation: updated review of the literature from 2003 through 2008. Arch Phys Med Rehabil. 2011.
10. Ros T, et al. Neurofeedback and the regulation of brain activity: a review. Neurosci Biobehav Rev. 2014.
11. Johansson BB. Brain plasticity in stroke rehabilitation. Stroke. 2011.
12. Enriquez-Geppert S, et al. Neurofeedback as a tool to modulate cognition and behavior. Neurosci Biobehav Rev. 2017.
13. Kleim J.A., Jones T.A. Principles of experience-dependent neural plasticity: implications for rehabilitation after brain damage. J Speech Lang Hear Res. 2008
14. Cramer S.C., et al. Harnessing neuroplasticity for clinical applications. Brain. 2011.
15. Grefkes C., Fink G.R. Reorganization of cerebral networks after stroke: new insights from neuroimaging. Brain. 2011.
16. Sitaram R., et al. Closed-loop brain training: the science of neurofeedback. Nat Rev Neurosci. 2017.
17. Ros T., Baars B.J., Lanius R.A., Vuilleumier P. Tuning pathological brain oscillations with neurofeedback. Nat Rev Neurosci. 2014.
18. Marzbani H., Marateb H.R., Mansourian M. Neurofeedback: a comprehensive review on system design, methodology and clinical applications. Basic Clin Neurosci. 2016.
19. Escolano C., Navarro-Gil M., Garcia-Campayo J., Congedo M., Minguez J. The effects of neurofeedback in cognitive performance: a systematic review. Brain Topogr. 2014.
20. Gruzelier J.H. EEG-neurofeedback for optimising performance: a review of cognitive and affective outcome. Neurosci Biobehav Rev. 2014.
21. Levin M.F., Kleim J.A., Wolf S.L. What do motor “recovery” and “compensation” mean in patients following stroke? Neurorehabil Neural Repair. 2009.
22. Johansson B.B. Current trends in stroke rehabilitation. A review with focus on brain plasticity. Acta Neurol Scand. 2011.
- Downloads
- Published
- 2026-03-30
- Issue
- Vol. 2 No. 3 (2026)
- Section
- Articles
- License
-
This work is licensed under a Creative Commons Attribution 4.0 International License.
