CHILDHOOD-ONSET IDIOPATHIC GENERALIZED EPILEPSIES: PATHOGENESIS, CLINICAL SPECTRUM, DIAGNOSIS, AND MODERN THERAPEUTIC APPROACHES
- Authors
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Muminova Ra’no Turaevna
Branch of Kazan Federal University in Jizzakh Jizzakh
Author
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Arzikulov Turakul Narzikulovich
Branch of the Republican Scientific Center for Emergency Medical
Author
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- Keywords:
- Idiopathic generalized epilepsy, childhood epilepsy, absence seizures, myoclonus, EEG, treatment
- Abstract
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Childhood-onset idiopathic generalized epilepsies (IGEs) represent a heterogeneous group of genetically determined epileptic syndromes characterized by generalized seizure types and the absence of structural brain abnormalities. These disorders include a spectrum of syndromes such as benign myoclonic epilepsy of infancy, childhood absence epilepsy, epilepsy with myoclonic-astatic seizures, and epilepsy with myoclonic absences. This review provides a comprehensive analysis of their pathophysiology, clinical manifestations, electroencephalographic features, differential diagnosis, and treatment strategies. Although many forms exhibit favorable outcomes, certain syndromes demonstrate pharmacoresistance and neurocognitive impairment, emphasizing the importance of early diagnosis and individualized management.
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- Published
- 2026-05-02
- Issue
- Vol. 2 No. 4 (2026)
- Section
- Articles
- License
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This work is licensed under a Creative Commons Attribution 4.0 International License.
