MODERN ASPECTS OF PERIODONTAL TISSUE CONDITIONS IN PATIENTS WITH LIVER DISEASES AND AFTER LIVER TRANSPLANTATION (LITERATURE REVIEW)
Keywords:
Periodontitis; liver diseases; liver transplantation; immunosuppression; microbiota; systemic inflammation; dysbiosis.Abstract
This literature review presents current data on the relationship between inflammatory periodontal diseases and chronic liver diseases, including the post-liver transplantation condition. Key pathogenetic mechanisms are discussed, including systemic inflammation, immune dysregulation, and dysbiotic changes in the oral microbiota. Clinical features of periodontitis in patients with liver pathology and transplant recipients are analyzed. The role of oral health status as an important prognostic factor and the need for an interdisciplinary approach to patient management are substantiated.
In Republic of Uzbekistan, the problem of chronic liver diseases remains highly relevant due to the high prevalence of viral hepatitis and metabolic disorders. National researchers also report a significant impact of systemic pathology on periodontal tissue conditions (Khamidov A.A., Yusupov Sh.Sh., 2019).








