THE ROLE OF THYROID HORMONES IN PROTEIN, LIPID, AND CARBOHYDRATE METABOLISM

Authors

  • Shoyusupova Shaxrizoda Shoxobiddin qizi

    Student of the Faculty of General Medicine, Tashkent State Medical University, Tashkent, Uzbekistan

    Author

  • Alisherova Mahliyo. A

    Assistant of the Department of Medical Radiology, Tashkent Medical Academy, Tashkent, Uzbekistan

    Author

Keywords:
Thyroid gland, thyroxine (T4), triiodothyronine (T3), metabolism, hypothyroidism, hyperthyroidism, iodine deficiency, hormones, energy metabolism, lipid metabolism, carbohydrate metabolism
Abstract

This article presents a comprehensive analysis of the crucial role of thyroid hormones—thyroxine (T4) and triiodothyronine (T3)—in regulating metabolic processes within the human body. The anatomical and physiological characteristics of the thyroid gland, along with hormone biosynthesis and their activation in peripheral tissues, are thoroughly described. Particular attention is given to T4 as the predominant circulating hormone in the bloodstream and its conversion into the biologically active form, T3, in most tissues.

References

1.Britannica, T. Editors of Encyclopaedia. (n.d.). Thyroid gland. In Encyclopædia Britannica. https://www.britannica.com/science/thyroid-gland

2.Cleveland Clinic. (n.d.). Thyroid hormone. https://my.clevelandclinic.org/health/articles/22391-thyroid-hormone

3.Chauhan, A., & Patel, S. S. (2021). Thyroid hormone and diabetes mellitus interplay: Making management of comorbid disorders complicated. Hormone and Metabolic Research, 53(10), 643–651. https://doi.org/10.1055/a-1634-9279

Diabetes & Endocrinology. Elsevier.

5.Sinha, R. A., Singh, B. K., & Yen, P. M. (2014). Thyroid hormone regulation of hepatic lipid and carbohydrate metabolism. Trends in Endocrinology & Metabolism, 25(10), 538–545. https://doi.org/10.1016/j.tem.2014.07.001

6.Brent, G. A. (2012). Mechanisms of thyroid hormone action. The Journal of Clinical Investigation, 122(9), 3035–3043. https://doi.org/10.1172/JCI60047

7.World Health Organization. (n.d.). Thyroid disorders. Georg Thieme Verlag KG.

8.UNICEF. (n.d.). Monitoring of salt iodization. https://www.unicef.org/

9.Endocrinology research—Reflecting on the past decade and looking to the next. (2020). Nature Reviews Endocrinology, 16(1), 1–2. https://doi.org/10.1038/s41574-019-0294-1

10.Global Iodine Network. (n.d.). Iodine deficiency. https://www.ign.org/

11.National Library of Medicine. (n.d.). Thyroid diseases. MedlinePlus. https://medlineplus.gov/thyroiddiseases.html

12.Sabatino, L., & Vassalle, C. (2021). Thyroid hormones and metabolism regulation: Which role on brown adipose tissue and browning process? Biomolecules, 11(11), 1582. https://doi.org/10.3390/biom11111582

13.MSD Manual. (n.d.). Thyroid gland. https://www.msdmanuals.com/

14.Pucci, E., Chiovato, L., & Pinchera, A. (2000). Thyroid and lipid metabolism. International Journal of Obesity, 24(S2), S109–S112. https://doi.org/10.1038/sj.ijo.0801292.

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Published
2026-05-08
Issue
Vol. 2 No. 5 (2026)
Section
Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

THE ROLE OF THYROID HORMONES IN PROTEIN, LIPID, AND CARBOHYDRATE METABOLISM. (2026). Eureka Journal of Health Sciences & Medical Innovation, 2(5), 103-112. https://eurekaoa.com/index.php/5/article/view/962