OBESITY-ASSOCIATED MENTAL DISORDERS: NEUROBIOLOGICAL, PSYCHOSOCIAL AND CLINICAL-PSYCHOPATHOLOGICAL DETERMINANTS (NARRATIVE REVIEW)

Authors
  • Talipova N. Sh.

    Tashkent State Medical University

    Author

  • Kevorkova M. A.

    Tashkent State Medical University

    Author

  • Zokirov M. M.

    Tashkent State Medical University

    Author

Keywords:
Obesity, depression, anxiety, mental disorders, inflammation, insulin resistance, stigmatization.
Abstract

Obesity is considered not only a metabolic disorder but also a condition closely associated with an increased risk of developing mental disorders. This article summarizes current evidence on biological, psychosocial, and genetic–epigenetic factors that increase the likelihood of psychopathology in patients with obesity. It is shown that chronic inflammation, insulin resistance, stress, stigmatization, emotional eating, body image disturbance, and early traumatic experiences form an interrelated system of risk factors. The review emphasizes the necessity of a comprehensive, multidisciplinary approach to the prevention and treatment of obesity and its comorbid mental disorders.

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Published
2026-05-09
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How to Cite

OBESITY-ASSOCIATED MENTAL DISORDERS: NEUROBIOLOGICAL, PSYCHOSOCIAL AND CLINICAL-PSYCHOPATHOLOGICAL DETERMINANTS (NARRATIVE REVIEW). (2026). Eureka Journal of Health Sciences & Medical Innovation, 2(5), 113-130. https://eurekaoa.com/index.php/5/article/view/975