MECHANO-BIOLOGICAL RESPONSE OF POLYLACTIC ACID-BASED BIOCOMPOSITES IN THE CONTEXT OF STRUCTURAL MATERIAL DESIGN

• Umida A. Ziyamukhamedova

  Doctor of Technical Sciences, Professor Kimyo International University in Tashkent, Uzbekistan

  Author

• Dilnoza A. Egamnazarova

  1st Year Master Student, Kimyo International University in Tashkent, Uzbekistan

  Author

Polylactic acid (PLA)-based biocomposites represent a promising class of materials for biomedical applications due to their biodegradability, biocompatibility, and structural tunability. In the present study, PLA biocomposites are analyzed from the perspective of mechano-biological response governed by material structural organization. The objective of this work is to establish the relationship between filler morphology, matrix phase structure, and interfacial interactions, and the resulting mechanical and biological behavior of the composite. It is demonstrated that mechanical characteristics of PLA-based biocomposites may act as active regulators of biological response rather than passive performance indicators. A structure–function design framework for PLA biocomposites intended for biomedical applications is proposed.

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