ACCURACY OF IMAGE-GUIDED TRU-CUT BIOPSY IN THE DIAGNOSIS OF PEDIATRICS TUMORS IN BASRA, IRAQ

Authors
  • Dr. Bashar Abdul Razzaq Molan

    M. B. CH.B, DMRD Iraqi Ministry of Health, Basrah Health Directorate Basrah Children Speciality Hospital, Radiology Department

    Author

  • Dr. Rashid Najm Jasim

    M.B.Ch.B., CABMS. \ (Radiology) Iraqi Ministry of Health, Dhi Qar Health Directorate. Head of health directorate, Dhi Qar, Iraq.

    Author

  • Dr.Mustafa Ghazi Saad

    M.B.Ch.B., CABMS. \ (Radiology) Iraqi Ministry of Health, Basra Health Directorate. Al Maoanie Teaching Hospital, Basra, Iraq.

    Author

  • Dr. Ali Qais Abdulkafi

    M.B.Ch.B., D.C.H. \ (Pediatrics) Iraqi Ministry of Health, Kirkuk Health Directorate, Director of the Technical Affairs Department, Kirkuk Teaching Hospital, Kirkuk, Iraq.

    Author

Keywords:
Tru-cut biopsy, image, pediatric tumors.
Abstract

Multi-modality image-guided core needle biopsy (ultrasound, computed tomography and magnetic resonance imaging) has become a mainstay in paediatric oncology to avoid invasive and time-consuming surgery while simultaneously improving the diagnostic accuracy and reducing the incidence of sequelae. But a tiny targeted piece has the same quantity and quality of abnormal parts as surgery does.
Objective: To evaluate the diagnostic reliability of image-guided core biopsy in soft tissue or bone tumours in paediatric patients.
Methods: This retrospective study included patients who had clinical and radiological examinations due to solid masses that were considered neoplastic or who were under follow-up oncology treatment with suspected metastasis. All patients underwent image-guided Tru-cut biopsies to confirm or rule out the diagnosis of tumour. The study began in September 2020 and will go until September 2025.
Results: The total number of patients included in the study was one hundred. Sixty-five were men and 35 were females, with a mean age of 1.9±2.4 years. The first trial in 90% of patients provided a sufficient tissue sample; the second trial was used for 10% of patients to collect enough tissue. A Tru-cut needle biopsy was the method of choice in 95 (95%) patients in both trials, whereas in 5 (5%) patients an open biopsy was performed. Of the patients diagnosed using tru-cut needle biopsies, forty (40%) were diagnosed with non-Hodgkin’s lymphoma, thirty (30%) with neuroblastoma, ten (10%) with osteosarcoma, ten (10%) with rhabdomyosarcoma, three (3%) with nephroblastoma and two (2%) had boney metastases. 95% of patients were appropriately diagnosed with a tru-cut needle biopsy.
Conclusion: image-guided percutaneous tru-cut needle biopsy allows for accurate and safe sampling of solid tumours in children. It can yield a reliable diagnosis in cases of solid abdominal tumours in children.

References

1.A. Bhushan, A. Gonsalves, J.U. Menon Current State of Breast Cancer Diagnosis, Treatment, and Theranostics Pharmaceutics, 13 (5) (2021), p. 723, 10.3390/pharmaceutics13050723 May 14 View at publisherView in ScopusGoogle Scholar [2]

2.T.K. Sahin, R. Ayasun, A. Rizzo, D.C. Guven Prognostic Value of Neutrophil-to-Eosinophil Ratio (NER) in Cancer: a Systematic Review and Meta-Analysis

Cancers (Basel), 16 (21) (2024), p. 3689, 10.3390/cancers16213689 Oct 31

View at publisherView in ScopusGoogle Scholar [3]

3.E.S. McDonald, A.S. Clark, J. Tchou, P. Zhang, G.M. Freedman Clinical diagnosis and management of breast cancer J. Nucl. Med, 57 (1) (2016), pp. 9S-16S, 10.2967/jnumed.115.157834 FebSuppl View at publisherGoogle Scholar

1.

[4]

4.E.D. Pisano, L.L. Fajardo, D.J. Caudry, N. Sneige, W.J. Frable, W.A. Berg, et al. Fine-needle aspiration biopsy of nonpalpable breast lesions in a multicenter clinical trial: results from the Radiologic Diagnostic Oncology Group V1

Radiology, 219 (3) (2001), pp. 785-792, 10.1148/radiology.219.3.r01jn28785

Jun View at publisherView in ScopusGoogle Scholar[5]

5.A. Rizzo, F.M. Schipilliti, F. DiCostanzo, S. Acquafredda, G. Arpino, F. Puglisi, et al.Discontinuation rate and serious adverse events of chemoimmunotherapy as neoadjuvant treatment for triple-negative breast cancer: a systematic review and meta-analysis ESMO Open, 8 (6) (2023), Article 102198, 10.1016/j.esmoop.2023.102198 Dec View PDFView articleView in ScopusGoogle Scholar[6]

6. . Rizzo, A. Cusmai, S. Acquafredda, F. Giovannelli, L. Rinaldi, A. Misino, et al.KEYNOTE-522, IMpassion031 and GeparNUEVO: changing the paradigm of neoadjuvant immune checkpoint inhibitors in early triple-negative breast cancer

Future Oncol, 18 (18) (2022), pp. 2301-2309, 10.2217/fon-2021-1647Jun View in ScopusGoogle Scholar [7]

7.S. Hari, S. Kumari, A. Srivastava, Sanjay Thulkar, S. Mathur, PrasadThotton Veedu Image guided versus palpation guided core needle biopsy of palpable breast masses: a prospective study Indian J. Med. Res, 143 (5) (2016), pp. 597-604, 10.4103/0971-5916.187108 Jan View in ScopusGoogle Scholar [8]

8. L. Liberman, T.L. Feng, D.D. Dershaw, E.A. Morris, A.F. Abramson US-guided core breast biopsy: use and cost-effectiveness Radiology, 208 (3) (1998), pp. 717-723, 10.1148/radiology.208.3.9722851 Sep View in ScopusGoogle Scholar [9]

9. R. Caputo, G. Buono, M. Piezzo, C. Martinelli, D. Cianniello, A. Rizzo, et al.

Sacituzumab Govitecan for the treatment of advanced triple negative breast cancer patients: a multi-center real-world analysis Front Oncol, 14 (2024), Article 1362641, 10.3389/fonc.2024.1362641 Mar 26 View in ScopusGoogle Scholar [10]

10.A. Sridharan, J.R. Eisenbrey, P. Machado, H. OjedaFournier, A. Wilkes, A. Sevrukov, et al.Quantitative analysis of vascular heterogeneity in breast lesions using contrast-enhanced 3-D harmonic and subharmonic ultrasound imaging

IEEE Trans Ultrason. Ferroelectr Freq. Control, 62 (3) (2015), pp. 502-510, 10.1109/tuffc.2014.006886 Mar View in ScopusGoogle Scholar [11]

11. S. Kaplan Automated whole breast ultrasound Radiol. Clin. North Am, 52 (3) (2014), pp. 539-546, 10.1016/j.rcl.2014.01.002 May View PDFView articleView in ScopusGoogle Scholar[12]

12. V.I. Shah, U. Raju, D. Chitale, V. Deshpande, N. Gregory, V. Strand False-negative core needle biopsies of the breast: an analysis of clinical, radiologic, and pathologic findings in 27 consecutive cases of missed breast cancer Cancer, 97 (8) (2003), pp. 1824-1831, 10.1002/cncr.11278 Apr 15[25]

13.C.D. Scopa, D. Koukouras, J. Spiliotis, J. Harkoftakis, S. Koureleas, D. Kyriakopoulou, et al.Comparison of fine needle aspiration and Tru-Cut biopsy of palpable mammary lesionsCancer Detect. Prev, 20 (6) (1996), pp. 620-624

PMID: 8939348View in ScopusGoogle Scholar[26]

14.S.Moharamipour, M. Aminifar, M.R. ForoughiGilvaee, P. Faranoush, R. Mahdavi, H. Abadijoo, et al.Hydroelectric actuator for 3-dimensional analysis of electrophoretic and dielectrophoretic behavior of cancer cells; suitable in diagnosis and invasion studies Biomater. Adv, 151 (2023), Article 213476, 10.1016/j.bioadv.2023.213476 May 31 View PDFView articleView in ScopusGoogle Scholar[27]

15.M. Ahmed, T.M. Ayub, R. Raza, M.B. Ghazipura, Abdul Rehman, L.S. Sherani Comparative analysis of the diagnostic accuracy of fine-needle aspiration cytology (FNAC) versus true-cut biopsy in the detection of malignancy within detectable breast Masses.

Downloads
Published
2026-06-09
Section
Articles
License
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

ACCURACY OF IMAGE-GUIDED TRU-CUT BIOPSY IN THE DIAGNOSIS OF PEDIATRICS TUMORS IN BASRA, IRAQ. (2026). Eureka Journal of Health Sciences & Medical Innovation, 2(6), 259-268. https://eurekaoa.com/index.php/5/article/view/1289

Most read articles by the same author(s)